Dr. Dharmendra Kumar Yadav: Assistant Professor at Department of Biologics, College of Pharmacy, Gachon University, Korea

Dr. Dharmendra Kumar Yadav is a globally recognized scientist, currently serving as an Assistant Professor at the Department of Biologics, College of Pharmacy, Gachon University, South Korea. With a Ph.D. in Biological Science from CSIR-Central Institute of Medicinal and Aromatic Plants (Lucknow, India), he is regarded as one of the world’s top 2% scientists. His research integrates molecular modeling, chemoinformatics, bioinformatics, and plasma medicine, focusing on computational approaches for drug discovery and therapeutic applications. His work explores the in-silico prediction of biological activities and the molecular mechanisms behind plasma’s interactions with biomolecules, particularly in cancer treatment. Dr. Yadav’s groundbreaking contributions to plasma chemistry and bioinformatics have positioned him at the forefront of these rapidly evolving fields.

Online Profiles

Google Scholar Profile

  • Citations: 4874 total, with 3868 since 2020.

  • h-index: 37 total, with 32 since 2020.

  • i10-index: 122 total, with 113 since 2020.

Dr. Yadav maintains a robust digital presence through platforms such as Google Scholar, ResearchGate, and LinkedIn, where his work on molecular dynamics simulations, plasma medicine, and drug design is extensively shared. His profiles serve as a bridge between his research and the broader scientific community, enabling collaborations with top universities and research institutes. He regularly engages in academic discourse, providing valuable insights into cutting-edge computational techniques and interdisciplinary research. Through these platforms, Dr. Yadav not only shares his findings but also mentors the next generation of scientists, fostering international collaborations and partnerships.

Education

Dr. Yadav’s educational background is grounded in interdisciplinary research, combining biological sciences with advanced computational techniques. He earned his Ph.D. in Biological Science in 2013, working on QSAR model development for anticancer compounds at CSIR-Central Institute of Medicinal and Aromatic Plants, affiliated with Jawaharlal Nehru University, India. His research during his doctorate focused on developing predictive models for natural compounds, aiming to assess their in-vitro and in-vivo anticancer activities. Prior to his Ph.D., Dr. Yadav obtained his M.Sc. in Biomedical Science from Bundelkhand University, Jhansi, India, where he laid the foundation for his career in computational biology and drug discovery.

Research Focus

Dr. Yadav’s research is multifaceted, spanning several cutting-edge areas of computational biology, chemistry, and medicine. At the core of his work is the development of predictive QSAR models aimed at the functional identification of DNA and protein motifs, leveraging statistical methods and machine learning algorithms. His research into plasma medicine focuses on understanding the interactions between reactive plasma species and cellular biomolecules, such as DNA, proteins, and phospholipids. By using computational techniques like molecular dynamics simulations and density functional theory (DFT), Dr. Yadav seeks to unravel the underlying mechanisms of plasma therapy, particularly for cancer treatment. His other areas of interest include nanotechnology and plasma-surface interactions, with a goal to improve the efficiency of plasma for chemical production and fuel synthesis.

Experience

Dr. Yadav has over 10 years of academic and professional experience in both research and teaching. Since March 2024, he has been an Assistant Professor at Gachon University, where he teaches and mentors undergraduate, master’s, and Ph.D. students in the fields of pharmaceutical sciences and computational biology. His academic journey also includes roles as Principal Scientist at Arontier Co. Ltd., where he worked on drug development projects, and Research Professor at Gachon University from 2016 to 2019. Prior to his academic tenure, Dr. Yadav gained international exposure as a Post-Doctoral Research Fellow at Hanyang University, Seoul, South Korea, and a CSIR-Research Associate at the University of Delhi. His diverse experience across academia, research institutions, and industry positions him as a leading expert in his field.

Research Timeline

  • 2021–2022: Co-Principal Investigator for an AI-based anticancer drug development project funded by Gachon University Hospital, focusing on the development of RET-targeted therapies.

  • 2017–2020: Led the National Research Foundation of Korea (NRF) funded project on plasma medicine, exploring its application in cancer therapy and the interaction of reactive species with biomolecules.

  • 2015–2028: As Principal Investigator, led a long-term project funded by the Science & Engineering Research Board (SERB) on QSAR and molecular docking of COX inhibitors.

  • 2014–2015: Worked as a Research Associate at University of Delhi, developing QSAR models for anticancer natural products and advancing drug discovery.

  • 2013–2014: Postdoctoral Fellow at Hanyang University, where he conducted advanced research in nanoscale characterization and the study of plasma interactions with materials.

Awards & Honors

Dr. Yadav’s exceptional contributions to molecular dynamics, drug design, and plasma medicine have earned him recognition as one of the top 2% scientists worldwide. He has received numerous prestigious awards, including research grants from major funding agencies such as the National Research Foundation of Korea (NRF) and Science & Engineering Research Board (SERB). His achievements in interdisciplinary research, particularly in computational biology and cancer therapy, have also led to invitations to deliver keynote speeches at international conferences. Dr. Yadav is highly regarded for his leadership in advancing computational tools for drug discovery and plasma applications in medicine.

Top-Noted Publications

Dr. Yadav’s academic work has been widely published in high-impact journals and presented at international conferences. His publications on molecular dynamics simulations of reactive oxygen species (ROS) in plasma medicine are among the most cited in the field. Notable publications include studies on the interaction of plasma-generated ROS with native and oxidized lipid membranes and their implications for cancer therapy. His research on QSAR modeling for anticancer compounds has influenced the development of new drug discovery approaches. Dr. Yadav’s contributions have significantly advanced the understanding of plasma-biomolecule interactions, making him a leading authority in computational toxicology and drug design.

  • Epigallocatechin 3-gallate: From green tea to cancer therapeutics

    • Citations: 193

    • Published: 2022

    • This one explores the potential of EGCG (a key component of green tea) in cancer treatment. Green tea’s bioactive compounds, like EGCG, have been linked to a variety of health benefits, including anti-cancer effects.

  • Biomedical features and therapeutic potential of rosmarinic acid

    • Citations: 168

    • Published: 2022

    • This article focuses on rosmarinic acid, which is found in herbs like rosemary and basil. It has antioxidant, anti-inflammatory, and antimicrobial properties, making it a great candidate for therapeutic applications.

  • Influence of reactive species on the modification of biomolecules generated from the soft plasma

    • Citations: 140

    • Published: 2015

    • This paper looks at how reactive species (like free radicals) interact with biomolecules, a topic of interest in plasma medicine and biotechnology.

  • Molecular dynamic simulations of oxidized skin lipid bilayer and permeability of reactive oxygen species

    • Citations: 118

    • Published: 2019

    • This publication discusses how reactive oxygen species (ROS) affect the permeability of skin lipid bilayers, which could have implications for skin health, drug delivery, and cosmetics.

  • Identification of novel acetylcholinesterase inhibitors designed by pharmacophore-based virtual screening, molecular docking and bioassay

    • Citations: 100

    • Published: 2018

    • This one focuses on drug discovery for neurodegenerative diseases by identifying compounds that inhibit acetylcholinesterase, an enzyme linked to Alzheimer’s disease.

Dharmendra Kumar Yadav, Chemistry, Best Researcher Award