Dr. Shyam Prakash: Prof ( Additional) at All India Institute of Medical Science, Ansari Nagar, New Delhi, India
Dr. Shyam Prakash is a senior biomedical researcher and Additional Professor at the Department of Laboratory Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi. With over 30 years of experience in clinical biochemistry and molecular diagnostics, he has established himself as a leading expert in the field of gastrointestinal, hepatic, and metabolic diseases. His translational research focuses on bridging laboratory science with patient care through the development of innovative diagnostic tools, point-of-care technologies, and molecular markers for early disease detection. Throughout his career, he has contributed significantly to public health research, diagnostics, and academic mentorship, mentoring over 22 MD and PhD students and authoring 75+ research papers.
Online Profiles
Citation Metrics
As of 2025, Dr. Shyam Prakash has received a total of 2,726 citations, with 1,021 citations since 2020. His h-index stands at 26, indicating substantial impact and consistent contributions across multiple publications. Additionally, his i10-index is 67, with 28 publications having received 10 or more citations since 2020. These metrics reflect the relevance and reach of his research in clinical biochemistry, molecular diagnostics, and translational medicine.
Education
Dr. Prakash received his foundational training in biochemistry and laboratory medicine, beginning his research career in 1993 as a Research Officer in Biochemistry at the Homoeopathic Drug Research Institute, Lucknow. He soon transitioned into forensic science and molecular diagnostics, working briefly at the Central Forensic Science Laboratory, Kolkata, before joining AIIMS in 1994. Over the years, he has continuously upgraded his scientific expertise through multidisciplinary collaborations and research leadership, particularly in the fields of molecular biology, clinical chemistry, and immunodiagnostics.
Research Focus
Dr. Prakash’s primary research interests span the molecular basis of liver and metabolic disorders, including non-alcoholic fatty liver disease (NAFLD), metabolic syndrome, and hepatitis B and C. He investigates the expression of tRNA-derived small RNAs, mitochondrial dysfunction, cytokine signaling, and nitric oxide pathways in chronic diseases. His lab has developed and validated micro-PCR technologies for rapid viral quantification (HBV, HCV, HIV), along with novel biosensors for anemia and salivary glucose detection. He is also involved in studying the role of micronutrients, vascular markers, and oxidative stress in gastrointestinal diseases and cancers.
Experience
Over the past three decades, Dr. Prakash has held several key positions. He joined AIIMS in 1994 as a Senior Scientist in the Department of Gastroenterology and Human Nutrition, where he served until 2014. He was then appointed Assistant Professor in the newly established Department of Laboratory Medicine, becoming Associate Professor in 2017 and Additional Professor in 2020. His earlier roles include Junior Scientific Officer at CFSL, Kolkata (1994), and Research Officer in Biochemistry at HDRI, Lucknow (1993–1994). This extensive experience has given him a deep understanding of both basic and applied biomedical science.
Research Timeline
Dr. Prakash’s research journey began in the early 1990s with clinical biochemistry and expanded into forensic and nutritional science. From 1994 to 2014, his work focused on gastrointestinal biology, where he contributed to understanding micronutrient deficiencies and inflammatory pathways in liver diseases. Since 2014, his research has evolved to include molecular diagnostics, small RNA profiling, oxidative stress biology, and biosensor technology. He now leads several national and collaborative projects funded by ICMR, DST, BIRAC, and AIIMS-IIT Delhi, focusing on advanced diagnostics for metabolic diseases and liver cancer.
Awards & Honors
Dr. Prakash is the recipient of numerous professional memberships and scientific honors. He is an Honorary Member of the Federation Internationale Law, Medicine, Ethics & Innovation (2024) and a Regular Member of the American Society for Biochemistry and Molecular Biology. He is also affiliated with the American Society of Cell Biology, Society for Free Radical Research, Indian Association of Biomedical Sciences, and the Society of Biological Chemists. His contributions have earned him positions on review panels for ICMR and DST, and he serves as a reviewer for the Indian Journal of Clinical Biochemistry and as a Board of Studies member at Poorvanchal University.
Top Noted Publication
Among his recent impactful publications is “Role of prokineticins and T-reg cells in obesity-associated metabolic oxidative dysregulation in NAFLD” (Scientific Reports, 2025), which provides insights into immune-metabolic interactions in liver disease. Another notable study, published in the IEEE Sensors Journal, presents a saliva-based non-invasive glucometer for diabetes management. He also co-authored a 2024 Sci Rep paper on HIV viral load quantification using micro-PCR, and contributed to landmark studies on anemia, PCOS, and biomarkers in metabolic and gastrointestinal diseases published in JAMA Netw Open, Lancet Regional Health, and MethodsX.
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Prevalence, Phenotypes, and Comorbidities of Polycystic Ovary Syndrome Among Indian Women
JAMA Network Open, 2024, Vol. 7(10): 1–15
Citations: 14
A major population-based study under the PCOS Study Group (PSGS) exploring epidemiological and hormonal patterns among Indian women, with Dr. Prakash as a core contributor. -
Forced Convection Heat Transfer in Doubly Connected Ducts
International Journal of Heat and Fluid Flow, 1987, Vol. 8(2): 107–110
Citations: 14
An early interdisciplinary engineering study co-authored by Dr. Prakash, contributing to thermal flow theory and heat transfer modeling. -
Prevalence of Sarcopenia and Its Determinants in People with Type 2 Diabetes
Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 2023, Vol. 17(12): 102902
Citations: 13
A collaborative clinical investigation identifying key predictors of muscle wasting in diabetic patients in northern India. -
Intravenous Iron Sucrose and Hematological Outcomes in Moderately Anemic Pregnant Women
Indian Journal of Public Health, 2020, Vol. 64(1): 11–16
Citations: 13
This study measured changes in hemoglobin, ferritin, and oxidative stress biomarkers following iron therapy in pregnant women. -
Performance and Emission Characteristics of Diesel Engines Using Biodiesel from Safflower and Milk Scum Oil
International Refereed Journal of Engineering and Science, 2014, Vol. 3(4): 103–112
Citations: 13
A cross-disciplinary energy study evaluating biodiesel alternatives for diesel engines, emphasizing Dr. Prakash’s early interest in environmental and engineering research. -
Takayasu’s Disease with Chest Pain, Fever, and Pleural Effusion
Journal of the Association of Physicians of India, 2005, Vol. 53: 722–724
Citations: 13
A clinical case report on the diagnostic complexity of a rare vascular disease, illustrating Dr. Prakash’s broad medical expertise.
Dr. Shyam Prakash’s strength for the Healthcare Innovation Award:
1. Development of Affordable Point-of-Care Diagnostics
Dr. Prakash has led the innovation of low-cost, rapid diagnostic tools such as micro-PCR platforms for HBV, HCV, and HIV, and non-invasive biosensors for anemia and salivary glucose, making advanced diagnostics more accessible in resource-limited settings.
2. Translational Research in Liver and Metabolic Diseases
His work bridges lab science and clinical care through the discovery of molecular markers in NAFLD, hepatitis, and metabolic syndrome, including studies on small RNAs, oxidative stress, and cytokine pathways that enable early detection and targeted treatment.
3. Interdisciplinary Innovation and Engineering Collaboration
By integrating biomedical science with engineering, Dr. Prakash has co-developed novel sensor technologies and bio-analytical devices in partnership with institutes like IIT Delhi, demonstrating a strong track record in translational tech innovation.
4. Public Health Impact Through Large-Scale Clinical Research
He has contributed to major national studies on PCOS, sarcopenia, and anemia, translating research into real-world healthcare improvements and shaping public health strategies, particularly in women’s health and chronic disease management.
5. Leadership in Research and Mentorship
With over 30 years at AIIMS, Dr. Prakash has mentored 22+ MD/PhD scholars, led ICMR and DST-funded projects, and served on national review panels, establishing a legacy of academic leadership, innovation, and capacity building in Indian healthcare.